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The viral protein corona directs viral pathogenesis and amyloid aggregation

Authors :
Kariem Ezzat
Maria Pernemalm
Sandra Pålsson
Thomas C. Roberts
Peter Järver
Aleksandra Dondalska
Burcu Bestas
Michal J. Sobkowiak
Bettina Levänen
Magnus Sköld
Elizabeth A. Thompson
Osama Saher
Otto K. Kari
Tatu Lajunen
Eva Sverremark Ekström
Caroline Nilsson
Yevheniia Ishchenko
Tarja Malm
Matthew J. A. Wood
Ultan F. Power
Sergej Masich
Anders Lindén
Johan K. Sandberg
Janne Lehtiö
Anna-Lena Spetz
Samir EL Andaloussi
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

The protein corona around artificial nanoparticles is known to influence activity and biological fate, the formation around viruses is less well understood. Here, the authors observe the formation of protein corona on viruses and study the effects this corona has on viral infectivity and on amyloid protein assembly.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.707b1edf615a4fe08fe6eacaded85b36
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-10192-2