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Relationships of serum MMP-7 and clinical characteristics in choledochal cyst children
- Source :
- BMC Surgery, Vol 24, Iss 1, Pp 1-9 (2024)
- Publication Year :
- 2024
- Publisher :
- BMC, 2024.
-
Abstract
- Abstract Background Matrix metalloproteinase-7 (MMP-7) is associated with biliary injury. This study aimed to evaluate the relationships of serum MMP-7 with clinical characteristics in choledochal cysts (CDC) children. Methods Between June 2020 and July 2022, we conducted a prospective study of CDCs who underwent one-stage definitive operation at our center. Serum MMP-7 was measured using an enzyme-linked immunosorbent assay. We evaluated the relationships between serum MMP-7 and age, laboratory tests, imaging examinations, liver fibrosis, MMP-7 expression, and perforation. Results A total of 328 CDCs were enrolled in the study, with a median serum MMP-7 of 7.67 ng/mL. Higher serum MMP-7 was correlated with younger age at diagnosis (p
- Subjects :
- MMP-7
Choledochal cyst
Liver fibrosis
Perforation
Children.
Surgery
RD1-811
Subjects
Details
- Language :
- English
- ISSN :
- 14712482
- Volume :
- 24
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- BMC Surgery
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7155641739da4e25a8ae5db1eea3f431
- Document Type :
- article
- Full Text :
- https://doi.org/10.1186/s12893-024-02488-y