A systematic review of population-based gingival health studies among children and adolescents with autism spectrum disorder

The prevalence of autism spectrum disorder (ASD) is close to 1% in the United States of America and other countries. Special attention should be given to oral health in individuals with ASD as they are often affected by oral diseases. However, gingival health in children with ASD and adolescents is controversial in terms of the severity of disease and number of people affected. Aim: To conduct a systematic review and meta-analysis to assess the gingival health status of children and adolescents with ASD. Methods: The search was conducted using eight databases for articles that met the inclusion and exclusion criteria. This search produced 742 relevant papers, but only five with sufficient data on gingival and plaque indices were eligible for inclusion in this systematic review and meta-analysis. Results: The homogeneity of the sample was tested using the Cohen Q test, which identified significant heterogeneity (P