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Prevalence of metabolic syndrome and associated factors among patients with chronic Chagas disease.

Authors :
Isis Gabrielli Gomes Xavier
Marcelo Carvalho Vieira
Luiz Fernando Rodrigues Junior
Gilberto Marcelo Sperandio da Silva
Paula Simplicio da Silva
Marcelo Teixeira de Holanda
Erica Rodrigues Maciel
Fernanda Martins Carneiro
Flavia Mazzoli-Rocha
Luiz Henrique Conde Sangenis
Fernanda de Souza Nogueira Sardinha Mendes
Alejandro Marcel Hasslocher-Moreno
Andrea Silvestre de Sousa
Andrea Rodrigues da Costa
Roberto Magalhães Saraiva
Pedro Emmanuel Alvarenga Americano do Brasil
Mauro Felippe Felix Mediano
Source :
PLoS ONE, Vol 16, Iss 4, p e0249116 (2021)
Publication Year :
2021
Publisher :
Public Library of Science (PLoS), 2021.

Abstract

The increase in life expectancy and the migration of individuals with Chagas disease (ChD) from rural to urban centers exposes them to the development of chronic-degenerative abnormalities that may increase the prevalence of metabolic syndrome (MetS). The present study aimed to identify the prevalence of MetS and its components in individuals with chronic ChD. This is a cross-sectional study with 361 patients of both sexes, aging >18 years, followed at a national reference center (Rio de Janeiro, Brazil). MetS diagnosis followed the International Diabetes Federation 2005 criteria. The association between the variables was determined through logistic regression models. The mean age was and 60.7±10.8 years. About half (56.2%) were female and the majority self-reported their race as mulatto (59.8%). The percentage of individuals with MetS was 40.4%. The variables independently associated with MetS were age (OR 1.06; 95%CI 1.04-1.09), high education levels (OR 0.36; 95%CI 0.17-0.79) and cardiac form with heart failure (OR 0.34; 95%CI 0.17-0.68). Therefore, a high prevalence of MetS was found in this Brazilian chronic ChD cohort. The identification of the associated factors can facilitate the development of effective approaches for preventing and managing MetS in ChD patients.

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
19326203
Volume :
16
Issue :
4
Database :
Directory of Open Access Journals
Journal :
PLoS ONE
Publication Type :
Academic Journal
Accession number :
edsdoj.7203956f70c14ef88ce73a78d1c16cf5
Document Type :
article
Full Text :
https://doi.org/10.1371/journal.pone.0249116