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Common and different lipidomes for lung cancer and tuberculosis: A comparative lipidomics analysis

Authors :
Beuy Joob
Viroj Wiwanitkit
Source :
Biomedical and Biotechnology Research Journal, Vol 3, Iss 4, Pp 233-235 (2019)
Publication Year :
2019
Publisher :
Wolters Kluwer Medknow Publications, 2019.

Abstract

Background: Of several lung disorders, the important diseases that are considered important burdens worldwide in the present day include lung cancer and tuberculosis. Sometimes, the diagnosis of the two mentioned lung problems is difficult. To make a differential diagnosis between negative and positive lungs for either lung cancer or tuberculosis is a critical point for further proper management. In the present day, the advanced novel biomedical technology allows the practitioner to assess the imprints of the pathological lungs. Methods: Lipidomics is a new biocochemioinformatics technique that can be useful lipidome imprint identification of medical disorders. Here, the authors perform a comparative lipidomcis analysis for lung cancer and tuberculosis. Results: There are 11 specific lipidomes for lung cancer, and there are 10 specific lipidomes for tuberculosis. There is only one overlapping lipidome, phosphatidylglycerol (PG) (34:1). Conclusion: According to the present analysis, the PG (34:1) is the specific lipidome that can help differentiate between lung cancer and tuberculosis.

Details

Language :
English
ISSN :
25889834 and 25889842
Volume :
3
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Biomedical and Biotechnology Research Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.725b0f0887b548e090b3cc2d8508f089
Document Type :
article
Full Text :
https://doi.org/10.4103/bbrj.bbrj_36_19