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Pd-catalyzed enantioselective intramolecular Heck reaction to access disubstituted dihydroisoquinolinone with a terminal olefin
- Source :
- Green Synthesis and Catalysis, Vol 2, Iss 4, Pp 374-376 (2021)
- Publication Year :
- 2021
- Publisher :
- KeAi Communications Co. Ltd., 2021.
-
Abstract
- A first palladium-catalyzed asymmetric intramolecular Heck reaction for the construction 3,4-dihydro-1-(2H)-isoquinolinone containing the quaternary carbon chiral center has been developed. The salient features of this reaction include high efficiency, high enantioselectivity, the novel chiral ligand and diverse transformations.
Details
- Language :
- English
- ISSN :
- 26665549
- Volume :
- 2
- Issue :
- 4
- Database :
- Directory of Open Access Journals
- Journal :
- Green Synthesis and Catalysis
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.732803d4564fb7916cd1148cefcfa4
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.gresc.2021.10.006