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Local anesthetics systemic toxicity in children: analysis of the French pharmacovigilance database

Authors :
Arnaud Schweitzer-Chaput
Delphine Callot
Naim Bouazza
Fabrice Lesage
Mehdi Oualha
Nathalie Paret
Marie Boyer-Gervoise
Jean-Marc Treluyer
Laurent Chouchana
Source :
BMC Pediatrics, Vol 23, Iss 1, Pp 1-10 (2023)
Publication Year :
2023
Publisher :
BMC, 2023.

Abstract

Abstract Purpose To characterize clinical profile of pediatric local anesthetic (LA) systemic toxicity (LAST) and to identify determinants of life-threatening outcomes. Methods Spontaneous reports notified to the French Pharmacovigilance Network were retrieved and followed by a case-by-case review, according to the following criteria: LA as suspected drug, age

Details

Language :
English
ISSN :
14712431
Volume :
23
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Pediatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.735cd5fdde2d46cdbca9a73c67dbe465
Document Type :
article
Full Text :
https://doi.org/10.1186/s12887-023-04126-7