Comorbid status in patients with osteomyelitis is associated with long-term incidence of extremity amputation

Introduction Osteomyelitis is associated with significant morbidity, including amputation. There are limited data on long-term amputation rates following an osteomyelitis diagnosis. We sought to determine the incidence of amputation in patients with osteomyelitis over 2 years.Research design and methods Observational cohort study of 1186 inpatients with osteomyelitis between 2004 and 2015 and stratified by osteomyelitis location status to evaluate the impact on amputation, mortality rates, readmission data, and inpatient days.Results Persons with diabetes had 3.65 times greater probability of lower extremity amputation (p