Labial adhesions caused by Stevens–Johnson syndrome

Vulvovaginal sequelae in Stevens–Johnson syndrome have been widely described in published literature, however, there is no consensus regarding effective preventive treatments. Labial minora synechiae as sequelae of Stevens–Johnson syndrome are rare, but can reduce patients' quality of life as a result of dysuria, urinary tract infection, and sexual dysfunction. Occasionally, sequelae can induce adenosis, and subsequently result in malignancy. Therefore, biopsy of the affected tissue in Stevens–Johnson syndrome patients with genital involvement should be considered after the acute phase has been resolved. Here, we report Stevens–Johnson syndrome with labial involvement in a 24-year-old woman who was treated with labial adhesiolysis. We recommend genital examination for all women with Stevens–Johnson syndrome to diagnose genital disease and avoid urinary tract infections and other sexual complications.