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Increased DNA methylation variability in type 1 diabetes across three immune effector cell types
- Source :
- Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
- Publication Year :
- 2016
- Publisher :
- Nature Portfolio, 2016.
-
Abstract
- The incidence of type 1 diabetes is increasing, potentially implicating non-genetic factors. Here the authors conduct an epigenome-wide association study in disease-discordant twins and find increased DNA methylation variability at genes associated with immune cell metabolism and the cell cycle.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 7
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.74847440186d44ba8513e31e9862b708
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/ncomms13555