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Current Scenario of Clinical Cancer Research in Latin America and the Caribbean

Authors :
Gustavo Gössling
Taiane F. Rebelatto
Cynthia Villarreal-Garza
Ana S. Ferrigno
Denisse Bretel
Raul Sala
Juliana Giacomazzi
William N. William
Gustavo Werutsky
Source :
Current Oncology, Vol 30, Iss 1, Pp 653-662 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, including a lack of oncology clinical trials. In this article, we will introduce the current status of the region’s clinical research in cancer, with a special focus on academic cancer research groups and investigator-initiated research (IIR) initiatives. Investigators in LAC have strived to improve cancer research despite drawbacks and difficulties in funding, regulatory timelines, and a skilled workforce. Progress has been observed in the representation of this region in clinical trial development and conduct, as well as in scientific productivity. However, most oncology trials in the region have been sponsored by pharmaceutical companies, highlighting the need for increased funding from governments and private foundations. Improvements in obtaining and/or strengthening the LAC cancer research group’s financing will provide opportunities to address cancer therapies and management shortcomings specific to the region. Furthermore, by including this large, ethnic, and genetically diverse population in the world’s research agenda, one may bridge the gap in knowledge regarding the applicability of results of clinical trials now mainly conducted in populations from the Northern Hemisphere.

Details

Language :
English
ISSN :
17187729 and 11980052
Volume :
30
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Current Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.74e5cd7f40c749d4be147d1c222d3c07
Document Type :
article
Full Text :
https://doi.org/10.3390/curroncol30010050