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Case series of intestinal microsporidiosis in non-HIV patients caused by Encephalitozoon hellem

Authors :
Céline Nourrisson
Samia Hamane
Julie Bonhomme
Marie-Fleur Durieux
Jean-Baptiste Foulquier
Sophie Lesthelle
Maxime Moniot
Marie-Elisabeth Bougnoux
Philippe Poirier
Source :
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Publication Year :
2023
Publisher :
Taylor & Francis Group, 2023.

Abstract

Intestinal microsporidiosis is most often caused by Enterocytozoon bieneusi, and to a lesser extent by species of the genus Encephalitozoon. Until now, Encephalitozoon hellem was not clearly known to induce disease restricted to the intestine, or rarely in HIV subjects or in tropical countries. We report here 11 cases of delineated intestinal microsporidioses due to E. hellem diagnosed in France in non-HIV patients. Briefly, all patients were immunocompromised. They all suffered from diarrhoea, associated in nearly 50% of cases with weight loss. Concerning treatment, 5/11 patients had a discontinuation or a decrease of their immunosuppressive therapy, and 4/11 received albendazole. All patients recovered. Five different genotypes were identified based on the rRNA ITS sequence.

Details

Language :
English
ISSN :
22221751
Volume :
12
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Emerging Microbes and Infections
Publication Type :
Academic Journal
Accession number :
edsdoj.75d24631e36541e6936097f759115676
Document Type :
article
Full Text :
https://doi.org/10.1080/22221751.2023.2258997