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Nanoencapsulation of Eggplant (Solanum melongena L.) Peel Extract in Electrospun Gelatin Nanofiber: Preparation, Characterization, and In Vitro Release

Authors :
Danya Elizabeth Estrella-Osuna
José Agustín Tapia-Hernández
Saúl Ruíz-Cruz
Enrique Márquez-Ríos
José de Jesús Ornelas-Paz
Carmen Lizette Del-Toro-Sánchez
Víctor Manuel Ocaño-Higuera
Francisco Rodríguez-Félix
María Isabel Estrada-Alvarado
Luis Alberto Cira-Chávez
Source :
Nanomaterials, Vol 12, Iss 13, p 2303 (2022)
Publication Year :
2022
Publisher :
MDPI AG, 2022.

Abstract

This study describes the preparation and characterization of eggplant peel extract-loaded electrospun gelatin nanofiber and study of its in vitro release. Results obtained by scanning electron microscopy (SEM) and transmission electronic microscopy (TEM) micrograph revealed that eggplant peel extract-loaded electrospun gelatin nanofiber is in nanometric range with an average diameter 606.7 ± 184.5 and 643.6 ± 186.7 nm for 20 and 33.3 mg mL−1 of extract addition, respectively. Moreover, the incorporation of extract improved morphology by being smooth, homogeneous, and without account formation compared to nanofibers without extract (control). Fourier transform-infrared (FT-IR) spectra indicated that interaction exists between electrospun gelatin nanofiber and eggplant peel extract by hydrogen bond interactions, mainly. Electrospun gelatin nanofibers showed encapsulation efficiency greater than 90% of extract and a maximum release of 95 and 80% for the medium at pH 1.5 and 7.5, respectively. Therefore, the electrospinning technique is a good alternative for the conservation of bioactive compounds present in the eggplant peel through electrospun gelatin nanofiber.

Details

Language :
English
ISSN :
20794991
Volume :
12
Issue :
13
Database :
Directory of Open Access Journals
Journal :
Nanomaterials
Publication Type :
Academic Journal
Accession number :
edsdoj.76da3899bc3b4907ae9d339ecfc3f4ef
Document Type :
article
Full Text :
https://doi.org/10.3390/nano12132303