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The impact of chirality on the analysis of alkaloids in plant

Authors :
Ngoc-Van Thi Nguyen
Kim-Ngan Huynh Nguyen
Kien Trung Nguyen
Kyeong Ho Kim
Hassan Y. Aboul-Enein
Source :
Pharmacia, Vol 68, Iss 3, Pp 643-656 (2021)
Publication Year :
2021
Publisher :
Pensoft Publishers, 2021.

Abstract

Most of the alkaloids are chiral compounds and are clinically administered as the racemic mixture, even though its enantiomers have been known to exert different pharmacological activity. The determination of the enantiomeric composition of alkaloid-containing plants is subject to severe attention from pharmacological and toxicological points of view. This review gives an overview of the chiral analysis of alkaloids that were used in theoretical studies and applications for plants in recent years.

Details

Language :
English
ISSN :
2603557X
Volume :
68
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Pharmacia
Publication Type :
Academic Journal
Accession number :
edsdoj.77524fd8b940cb84f94bcb843b2ccb
Document Type :
article
Full Text :
https://doi.org/10.3897/pharmacia.68.e71101