Back to Search
Start Over
Preparation of 6-Substituted Quinoxaline JSP-1 Inhibitors by Microwave Accelerated Nucleophilic Substitution
- Source :
- Molecules, Vol 11, Iss 12, Pp 988-999 (2006)
- Publication Year :
- 2006
- Publisher :
- MDPI AG, 2006.
-
Abstract
- A small library of 6-aminoquinoxalines has been prepared by nucleophilic substitution of 6-fluoroquinoxaline with amines and nitrogen-containing heterocycles under computer-controlled microwave irradiation. Some compounds were found to be potent inhibitors of JNK Stimulatory Phosphatase-1 (JSP-1) in an in vitro biological assay.
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 11
- Issue :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.77cd938c9528495ab68ffa53acd23e11
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/11120988