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BMI-adjusted adipose tissue volumes exhibit depot-specific and divergent associations with cardiometabolic diseases

Authors :
Saaket Agrawal
Marcus D. R. Klarqvist
Nathaniel Diamant
Takara L. Stanley
Patrick T. Ellinor
Nehal N. Mehta
Anthony Philippakis
Kenney Ng
Melina Claussnitzer
Steven K. Grinspoon
Puneet Batra
Amit V. Khera
Source :
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Publication Year :
2023
Publisher :
Nature Portfolio, 2023.

Abstract

Different location of adipose tissue may have different consequences to cardiometabolic risk. Here the authors report that deep learning enabled accurate prediction of specific adipose tissue volumes, and that after adjustment for BMI, visceral adiposity was associated with increased risk of cardiometabolic disease, while gluteofemoral adiposity was associated with reduced risk.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7844d42ac8a4868b82bf39c7f4b10d7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-35704-5