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The clinical features, treatment and prognosis of neutropenic fever and Coronavirus disease 2019 results of the multicentre teos study

Authors :
Dilşah Başkol Elik
Şafak Kaya
Sevil Alkan
Tuna Demirdal
Alper Sener
Selçuk Kaya
Özlem Güzel Tunçcan
Bircan Kayaaslan
Rahmet Güner
Fatma Eser
Hasip Kahraman
Serhat Birengel
Elif Mukime Sarıcaoğlu
Esma Eroğlu
Fatma Çölkesen
Erman Öztürk
Hande Berk Cam
Çiğdem Mermutluoğlu
Şafak Özer Balin
Gülden Sincan
Nilgün Altın
Uluhan Sili
Bedia Mutay Suntur
Tuğba Arslan Gülen
Burak Deveci
Rabin Saba
Şaban İncecik
Gülden Eser Karlıdağ
Elif Hakko
Damla Akdağ
Hüseyin Aytaç Erdem
Hilal Sipahi
Candan Çicek
Mehmet Sezai Taşbakan
Meltem Taşbakan
Hüsnü Pullukçu
Tansu Yamazhan
Bilgin Arda
Sercan Ulusoy
Oguz Resat Sipahi
Source :
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Publication Year :
2024
Publisher :
Nature Portfolio, 2024.

Abstract

Abstract This multicentre (22 centres in Turkey) retrospective cohort study aimed to assess the clinical outcomes of patients with neutropenic fever and SARS-CoV-2 positivity. Study period was 15 March 2020–15 August 2021. A total of 170 cases (58 female, aged 59 ± 15.5 years) that fulfilled the inclusion criteria were included in the study. One-month mortality rate (OMM) was 44.8%. The logistic regression analysis showed the following significant variables for the mentioned dependent variables: (i) achieving PCR negativity: receiving a maximum of 5 days of favipiravir (p = 0.005, OR 5.166, 95% CI 1.639–16.280); (ii) need for ICU: receiving glycopeptide therapy at any time during the COVID-19/FEN episode (p = 0.001, OR 6.566, 95% CI 2.137–20.172), the need for mechanical ventilation (p

Subjects

Subjects :
Medicine
Science

Details

Language :
English
ISSN :
20452322
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.78519889e2af4f3b8f91d2ad66134177
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-024-55886-w