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Admission blood glucose and 10-year mortality among patients with or without pre-existing diabetes mellitus hospitalized with heart failure

Authors :
Osnat Itzhaki Ben Zadok
Ran Kornowski
Ilan Goldenberg
Robert Klempfner
Yoel Toledano
Yitschak Biton
Enrique Z. Fisman
Alexander Tenenbaum
Gregory Golovchiner
Ehud Kadmon
Alexander Omelchenko
Tuvia Ben Gal
Alon Barsheshet
Source :
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-9 (2017)
Publication Year :
2017
Publisher :
BMC, 2017.

Abstract

Abstract Background High admission blood glucose (ABG) level has been associated with a poor short-term outcome among non-diabetic patients with heart failure (HF). We aimed to investigate the association between ABG levels and long-term (10 years) mortality in patients with or without pre-existing diabetes mellitus (DM) admitted with HF. Methods We analyzed data on 1811 patients with DM and 2182 patients without pre-existing DM who were hospitalized with HF during a prospective national survey. The relationship between ABG and 10-year mortality was assessed using the Cox proportional hazard model adjusting for multiple variables. ABG was analyzed both as a categorical (200 mg/dL) and as a continuous variable. Results At 10 years of follow-up the cumulative probability of mortality was 85 and 78% among patients with DM and patients with no pre-existing DM (p 200 mg/dL had an increased mortality risk (>200 mg/dL versus 200 mg/dL is associated with increased mortality risk.

Details

Language :
English
ISSN :
14752840
Volume :
16
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Cardiovascular Diabetology
Publication Type :
Academic Journal
Accession number :
edsdoj.7890701196764f9a8b47291a4faad484
Document Type :
article
Full Text :
https://doi.org/10.1186/s12933-017-0582-y