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Wells’ Syndrome Successfully Treated with Colchicine

Authors :
Álvaro Iglesias Puzas
Laura Mesa Álvarez
Ángeles Flórez Menéndez
Susana Romero Yuste
Olga Prieto Gómez
Source :
Case Reports in Dermatology, Vol 9, Iss 2, Pp 65-69 (2017)
Publication Year :
2017
Publisher :
Karger Publishers, 2017.

Abstract

Eosinophilic cellulitis is an uncommon, inflammatory and chronic disorder of unknown etiology. Corticosteroids are currently considered as the first-line treatment but they are not without significant disadvantages such as contraindications in steroid-resistant cases and patients with frequent recurrences. We report a patient suffering from Wells’ syndrome with a 24-year history of symptomatic and generalized skin lesions. After consultation in our department, treatment with colchicine 1 mg/day was prescribed resulting in large clinical improvement. No side effects have been recorded. To our knowledge, this is an original disease approach. Although small, our clinical experience supports the inclusion of colchicine in the drug armamentarium when treating patients suffering from Wells’ syndrome. Indeed, its excellent safety profile makes it very attractive for patients with frequent recurrent episodes who need secure options for the medium- and long-term disease control.

Details

Language :
English
ISSN :
16626567 and 00047775
Volume :
9
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Case Reports in Dermatology
Publication Type :
Academic Journal
Accession number :
edsdoj.78960a7046ed451b94687349f960c546
Document Type :
article
Full Text :
https://doi.org/10.1159/000477756