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Efficacy of compound betamethasone combined with ropivacaine in iliac fascial space nerve block analgesia

Authors :
Fan Miao
Huimiao Wang
Zhong Liu
Kexin Wang
Wanling Wang
Xinhe Guo
Chenjia Zhang
Chao Yu
Tu Shen
Source :
Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)
Publication Year :
2025
Publisher :
Nature Portfolio, 2025.

Abstract

Abstract To explore the anesthetic efficacy of ropivacaine combined with compound betamethasone in iliac fascial space nerve block analgesia (IFNBA) in patients receiving artificial femoral head replacement (AFHR), and to provide a theoretical basis for the selection of clinical anesthetic drugs. From January 2022 to June 2022, 70 patients requiring IFNBA analgesia undergoing AFHR surgery at our hospital were included in this prospective study. Using Excel randomization, 70 patients were divided into study group (n = 35) and control group (n = 35). The study group received ropivacaine combined with compound betamethasone analgesia regimen, while the control group only received ropivacaine analgesia regimen. In addition to patients’ general baseline clinical characteristics, outcomes indicators included preoperative and postoperative visual analogue scale (VAS) pain scores, preoperative and postoperative Ramsay sedation scores, preoperative and postoperative levels of inflammatory cytokines, duration of analgesia and patient satisfaction in both groups were collected. At 12 h and 24 h after surgery, the static and dynamic VAS pain score of the study group was significantly lower than that of the control group (P

Details

Language :
English
ISSN :
20452322
Volume :
15
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.78a8fc721b845bba2b8717625d19dc1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41598-025-85512-2