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Controlling Shapes in a Coaxial Flow Focusing Microfluidic Device: Experiments and Theory

Authors :
Romen Rodriguez-Trujillo
Yu-Han Kim-Im
Aurora Hernandez-Machado
Source :
Micromachines, Vol 11, Iss 1, p 85 (2020)
Publication Year :
2020
Publisher :
MDPI AG, 2020.

Abstract

A coaxial flow focusing PDMS (polydimethylsiloxane) microfluidic device has been designed and manufactured by soft lithography in order to experimentally study a miscible inner flow. We studied a coaxially focused inner flow (formed by an aqueous fluorescein solution) which was fully isolated from all microchannel surfaces by an additional water outer flow. Different flow rates were used to produce a variety of flow ratios and a 3D reconstruction of the cross-section was performed using confocal microscope images. The results showed an elliptical section of the coaxially focused inner flow that changes in shape depending on the flow rate ratio applied. We have also developed a mathematical model that allows us to predict and control the geometry of the coaxially focused inner flow.

Details

Language :
English
ISSN :
2072666X
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Micromachines
Publication Type :
Academic Journal
Accession number :
edsdoj.793b6f7d7d47430abc1d0ce0ae156aaf
Document Type :
article
Full Text :
https://doi.org/10.3390/mi11010085