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Nutraceutical prospective: The synergetic mechanism of action of inositols and resveratrol on metabolic syndrome

Nutraceutical prospective: The synergetic mechanism of action of inositols and resveratrol on metabolic syndrome

Authors :
Malvasi Antonio
Tinelli Andrea
Baldini Domenico
Iannitti Rossana G.
Fioretti Bernard
Source :
The EuroBiotech Journal, Vol 2, Iss 1, Pp 35-38 (2018)
Publication Year :
2018
Publisher :
Sciendo, 2018.

Abstract

It has been known that inositols function as insulin second messengers and mediate different insulin-dependent processes and are a valid natural, non-pharmaceutical alternative to contrast insulin-resistance as well as associated metabolic syndrome in women with Polycystic ovarian disease (PCOS). Several studies also have shown positive effects of resveratrol in reducing glucose and lipid concentrations in patients. Recently, clinical evidence has proven that an D-chiro-inositol/resveratrol combination has a potential role to play in maintaining metabolic and endocrine health, however no large clinical trials have demonstrated the medical effectiveness of the combination, and the combined mode of action remains poorly discussed. Herein, we address the hypothesis of a synergistic mechanism adopted by D-chiro-inositol and resveratrol in reducing insulin resistance and hyperlipidemia and thus showing a greater therapeutic potential compared to treatment with inositol’s alone.

Details

Language :
English
ISSN :
2564615X
Volume :
2
Issue :
1
Database :
Directory of Open Access Journals
Journal :
The EuroBiotech Journal
Publication Type :
Academic Journal
Accession number :
edsdoj.79600ad9deae4cc59ac8d61df6ae235d
Document Type :
article
Full Text :
https://doi.org/10.2478/ebtj-2018-0006