Methicillin-resistant Staphylococcus aureus in HIV-infected patients

Alicia I Hidron1,2, Russell Kempker2, Abeer Moanna1,2, David Rimland1,21Atlanta Veterans Affairs Medical Center, Decatur, GA, USA; 2Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USAAbstract: Concordant with the emergence of methicillin-resistant Staphylococcus aureus (MRSA) in the community setting, colonization and infections with this pathogen have become a prevalent problem among the human immunodeficiency virus (HIV)-positive population. A variety of different host- and, possibly, pathogen-related factors may play a role in ­explaining the increased prevalence and incidence observed. In this article, we review ­pathophysiology, ­epidemiology, clinical manifestations, and treatment of MRSA in the ­HIV-infected population.Keywords: MRSA, Staphylococcus aureus, HIV, resistance