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Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

Authors :
Yujian Chen
Kaidi Yang
Ya Huang
Xuejiao Wang
Yali Zhao
Ping Ping
Shasha Guan
Shihui Fu
Source :
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Publication Year :
2023
Publisher :
Wiley, 2023.

Abstract

Abstract Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older adults. This study aimed to investigate the associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults. In this cross‐sectional study, serum lipids were biochemically measured among 606 oldest‐old adults and 653 centenarians, and cognitive function was evaluated using mini‐mental state examination (MMSE). Multivariate linear and logistic regression analyses were performed to explore the associations between serum lipids and cognitive impairment. Results showed participants with cognitive impairment had lower total cholesterol (TC) levels compared with those without cognitive impairment (p

Details

Language :
English
ISSN :
26882663
Volume :
4
Issue :
5
Database :
Directory of Open Access Journals
Journal :
MedComm
Publication Type :
Academic Journal
Accession number :
edsdoj.7a38b4cdc554189a15178f36725b582
Document Type :
article
Full Text :
https://doi.org/10.1002/mco2.362