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A randomized and open-label phase II trial reports the efficacy of neoadjuvant lobaplatin in breast cancer

Authors :
Xiujuan Wu
Peng Tang
Shifei Li
Shushu Wang
Yueyang Liang
Ling Zhong
Lin Ren
Ting Zhang
Yi Zhang
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Triple-negative breast cancer (TNBC) is one of the most aggressive and difficult to treat types of breast cancer. Here, a phase 2 clinical trial in TNBC patients reveals that the addition of lobaplatin to docetaxel and epirubicin regime improves pCR and ORR rates with tolerable side-effects.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7abdbe810517401892ad3cece4d6b05b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-03210-2