SARS-CoV-2 Spike-specific IFN-γ T-cell Response After COVID-19 Vaccination in Patients With Chronic Kidney Disease, on Dialysis, or Living With a Kidney Transplant

Authors :: Céline Imhof, MD
A. Lianne Messchendorp, MD, PhD
Marieke van der Heiden, PhD
Carla C. Baan, PhD
Renate G. van der Molen, PhD
Ester B. M. Remmerswaal, PhD
Rory D. de Vries, PhD
Dimitri A. Diavatopoulos, PhD
Annemarie Boerma, MSc
Femke J. Bakker, BSc
Emily Oosterhout, BSc
Frederike J. Bemelman, MD, PhD
Luuk B. Hilbrands, MD, PhD
Marlies E. J. Reinders, MD, PhD
Ron T. Gansevoort, MD, PhD
Jan-Stephan Sanders, MD, PhD
Debbie van Baarle, PhD
on behalf of RECOVAC Consortium
Source :: Transplantation Direct, Vol 8, Iss 11, p e1387 (2022)
Publication Year :: 2022
Publisher :: Wolters Kluwer, 2022.
Abstract: Background. Studies have shown that coronavirus disease 2019 (COVID-19) vaccination is associated with a lower humoral response in vulnerable kidney patients. Here, we investigated the T-cell response following COVID-19 vaccination in kidney patients compared with controls. Methods. Patients with chronic kidney disease (CKD) stage G4/5 [estimated glomerular filtration rate

Full Text Access

Tools