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Presumed Retinal Metastasis from Lung Adenocarcinoma: A Case Report and Literature Review

Authors :
Gökçen Özcan
Ahmet Kaan Gündüz
Ibadulla Mirzayev
Ayhan Sağlik
Source :
Case Reports in Ophthalmological Medicine, Vol 2021 (2021)
Publication Year :
2021
Publisher :
Hindawi Limited, 2021.

Abstract

A 63-year-old Caucasian man with metastatic lung adenocarcinoma undergoing chemotherapy and external radiotherapy was referred for routine eye examination. Although he was asymptomatic, ocular examination revealed a relatively well-circumscribed whitish retinal lesion measuring 0.5×0.5×0.5 mm located along the inferotemporal vascular arcade in the right eye. Optical coherence tomography (OCT) showed a hyperreflective dome-shaped lesion occupying the inner retinal layers with few hyperreflective dots overlying the retina in the posterior vitreous consistent with tumor cells. Fluorescein angiography revealed early hyperfluorescence and late staining without leakage at the lesion site. A diagnosis of presumed retinal metastasis from lung adenocarcinoma was made. At 2 months follow-up after completion of chemotherapy, the retinal lesion was found to have regressed completely leaving minor irregularities in the inner retinal layers on OCT. To date, there have been only 41 cases of carcinoma metastasis to the retina reported in the literature including the current case. Despite its rarity, retinal metastasis should be considered in the differential diagnosis of a white-yellow retinal mass with/without overlying vitreous cells especially in patients with a history of systemic cancer.

Subjects

Subjects :
Ophthalmology
RE1-994

Details

Language :
English
ISSN :
20906722 and 20906730
Volume :
2021
Database :
Directory of Open Access Journals
Journal :
Case Reports in Ophthalmological Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.7b6d06562f174af5a6d0a3017fa56e2b
Document Type :
article
Full Text :
https://doi.org/10.1155/2021/6615284