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Multiplexed live-cell profiling with Raman probes

Authors :
Chen Chen
Zhilun Zhao
Naixin Qian
Shixuan Wei
Fanghao Hu
Wei Min
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Currently relatively few functional probes for Raman-based live-cell profiling exist. Here the authors build on their previous ultra-bright Raman dots to devise a 14-plexed Raman probe panel to quantify cell surface proteins, endocytosis activities and metabolic dynamics of single live cells.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7c2db342937a4bf5bc045156cf135ef1
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-23700-0