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The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts
- Source :
- Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
- Publication Year :
- 2018
- Publisher :
- Nature Portfolio, 2018.
-
Abstract
- Many microRNA encoding regions are within introns of other coding genes, and yet the molecular or functional interaction between the two is unclear. This study shows that miR-128′s function is opposed by its host gene ARPP21, and they have complementary effects on neuronal development.
- Subjects :
- Science
Subjects
Details
- Language :
- English
- ISSN :
- 20411723
- Volume :
- 9
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nature Communications
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7c8b8c16051e47579746c26c47d7c3ac
- Document Type :
- article
- Full Text :
- https://doi.org/10.1038/s41467-018-03681-3