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Diamond-Like Carbon Depositing on the Surface of Polylactide Membrane for Prevention of Adhesion Formation During Tendon Repair
- Source :
- Nano-Micro Letters, Vol 16, Iss 1, Pp 1-22 (2024)
- Publication Year :
- 2024
- Publisher :
- SpringerOpen, 2024.
-
Abstract
- Highlights The anti-adhesion effect of polylactic acid (PLA) membrane with diamond-like carbon (DLC) depositing is 44.72%, enhanced by 23.11% compared to PLA. DLC deposited on PLA membranes has been shown to effectively reduce the levels of reactive oxygen species, leading to a decrease in the expression of pro-inflammatory cytokines within peritendinous adhesion tissue. DLC decelerates PLA biodegradation and lactic production, which reduces the number of CD68+CD206+ macrophages within peritendinous adhesion tissue.
Details
- Language :
- English
- ISSN :
- 23116706 and 21505551
- Volume :
- 16
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Nano-Micro Letters
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7dd95529c10475093fe268e71144b18
- Document Type :
- article
- Full Text :
- https://doi.org/10.1007/s40820-024-01392-7