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Conformation and dynamics of soluble repetitive domain elucidates the initial β-sheet formation of spider silk

Authors :
Nur Alia Oktaviani
Akimasa Matsugami
Ali D. Malay
Fumiaki Hayashi
David L. Kaplan
Keiji Numata
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

β-sheet structure underlies the mechanical properties of spider silk but the mechanism to form β-sheet from soluble silk protein during transition into insoluble fibers has not been elucidated. Here the authors unravel the mechanism of β-sheet formation using NMR and circular dichroism spectroscopy.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7dec962a6e3241d294a8b3fa08fe5322
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-04570-5