Back to Search Start Over

Complete blood count-based inflammatory score (CBCS) is a novel prognostic marker for gastric cancer patients after curative resection

Authors :
Jian-Xian Lin
Jun-Peng Lin
Jian-Wei Xie
Jia-bin Wang
Jun Lu
Qi-Yue Chen
Long-long Cao
Mi Lin
Ruhong Tu
Chao-Hui Zheng
Chang-Ming Huang
Ping Li
Source :
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Publication Year :
2020
Publisher :
BMC, 2020.

Abstract

Abstract Background We sought to investigate the prognostic value of complete blood count (CBC)-based biomarkers for patients with resectable gastric cancer (GC). Methods Patients with GC who underwent primary surgical resection between December 2008 and December 2013 were included. The estimated area under the curve (AUC) and multivariate Cox regression models were used to identify the best CBC-based biomarker. Time-dependent receiver operating characteristic (t-ROC) curve analysis was used to predict overall survival and compare the prognostic impact. Results In the 1810 patients analyzed, the median follow-up period was 51.0 months (range 1–101 months). Based on multivariate analysis, the lymphocyte-monocyte ratio (LMR) and hemoglobin (Hb) level were independent prognostic factors (both P

Details

Language :
English
ISSN :
14712407
Volume :
20
Issue :
1
Database :
Directory of Open Access Journals
Journal :
BMC Cancer
Publication Type :
Academic Journal
Accession number :
edsdoj.7e67006d016f470086b0dcc942fb115d
Document Type :
article
Full Text :
https://doi.org/10.1186/s12885-019-6466-7