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Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia
- Source :
- Haematologica, Vol 107, Iss 5 (2021)
- Publication Year :
- 2021
- Publisher :
- Ferrata Storti Foundation, 2021.
-
Abstract
- Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the nucleotide sequences of lncRNA in AML patients is unknown. Herein, we analyzed total RNA sequencing data of 377 younger adults (aged
- Subjects :
- Diseases of the blood and blood-forming organs
RC633-647.5
Subjects
Details
- Language :
- English
- ISSN :
- 03906078 and 15928721
- Volume :
- 107
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Haematologica
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.7f9bf447eead48ccb2195be68f8f7b08
- Document Type :
- article
- Full Text :
- https://doi.org/10.3324/haematol.2021.266643