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Pharmacological properties of Chebulinic acid and related ellagitannins from nature: An emerging contemporary bioactive entity

Authors :
Ashwani K. Dhingra
Bhawna Chopra
Ajmer Singh Grewal
Kumar Guarve
Source :
Pharmacological Research - Modern Chinese Medicine, Vol 5, Iss , Pp 100163- (2022)
Publication Year :
2022
Publisher :
Elsevier, 2022.

Abstract

Terminalia chebula, (Family: Combretaceae) is a medicinally active plant possess a wide spectrum of biological activities and contain numerous bioactive phytoconstituents like phenolic compounds, hydrolysable tannins, and flavonoids, therefore it may be considers as a good therapeutic alternative. Chebulinic acid, an ellagitannin was isolated from the fruits of Terminalia chebula and was known to possess numerous biological activities including anti-tumor activity, anti-atherogenic, anti-fibrotic, anti-inflammatory, antiulcer, antioxidant, hepatoprotective, antidiabetic, and antiviral etc. The present chapter describes the various analytical methods, structure elucidation, biological activities, pharmacokinetic, patents and various marketed formulations. Thus, chebulinic acid and related derivatives of Terminalia chebula and other plant species possess numerous pharmacological which paves way for further studies.

Details

Language :
English
ISSN :
26671425
Volume :
5
Issue :
100163-
Database :
Directory of Open Access Journals
Journal :
Pharmacological Research - Modern Chinese Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.7fb5c211f29d4317a3b45fa62f70c608
Document Type :
article
Full Text :
https://doi.org/10.1016/j.prmcm.2022.100163