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Single-cell analysis of diverse immune phenotypes in malignant pleural effusion

Authors :
Zhong-Yin Huang
Ming-Ming Shao
Jian-Chu Zhang
Feng-Shuang Yi
Juan Du
Qiong Zhou
Feng-Yao Wu
Sha Li
Wei Li
Xian-Zhen Huang
Kan Zhai
Huan-Zhong Shi
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

Detailed immune cell subset identification in human lung (malignant pleural effusion) MPE is important for diagnosis and prognosis. Here the authors use single cell RNA sequencing to identify immune cell types within MPE and show differential gene expression compared to circulating immune cells in blood.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.7febab54f7cc4a74aadb0165585269a7
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27026-9