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Arabidopsis ACINUS is O-glycosylated and regulates transcription and alternative splicing of regulators of reproductive transitions

Authors :
Yang Bi
Zhiping Deng
Weimin Ni
Ruben Shrestha
Dasha Savage
Thomas Hartwig
Sunita Patil
Su Hyun Hong
Zhenzhen Zhang
Juan A. Oses-Prieto
Kathy H. Li
Peter H. Quail
Alma L. Burlingame
Shou-Ling Xu
Zhi-Yong Wang
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

AtACINUS is an Arabidopsis homolog of a mammalian splicing regulator and previously found to be O-GlcNAcyated. Here Bi et al. characterize the interactors and targets of AtACINUS, show it is required for development and stress responses and provide evidence that its O-glycosylation affects alternative splicing.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.80731db86bc4dd79d72a501630e0b75
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-20929-7