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Various screening and diagnosis approaches for gestational diabetes mellitus and adverse pregnancy outcomes: a secondary analysis of a randomized non-inferiority field trial
- Source :
- BMJ Open Diabetes Research & Care, Vol 11, Iss 6 (2023)
- Publication Year :
- 2023
- Publisher :
- BMJ Publishing Group, 2023.
-
Abstract
- Introduction We evaluate which screening and diagnostic approach resulted in the greatest reduction in adverse pregnancy outcomes due to increased treatment.Research design and methods This study presents a secondary analysis of a randomized community non-inferiority trial conducted among pregnant women participating in the GULF Study in Iran. A total of 35 430 pregnant women were randomly assigned to one of the five prespecified gestational diabetes mellitus (GDM) screening protocols. The screening methods included fasting plasma glucose (FPG) in the first trimester and either a one-step or a two-step screening method in the second trimester of pregnancy. According to the results, participants were classified into 6 groups (1) First-trimester FPG: 100–126 mg/dL, GDM diagnosed at first trimester; (2) First trimester FPG: 92–99.9 mg/dL, GDM diagnosed at first trimester; (3) First trimester FPG: 92–99.9 mg/dL, GDM diagnosed at second trimester; (4) First trimester FPG: 92–99.9 mg/dL, healthy at second trimester; (5) First trimester FPG
- Subjects :
- Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Subjects
Details
- Language :
- English
- ISSN :
- 20524897
- Volume :
- 11
- Issue :
- 6
- Database :
- Directory of Open Access Journals
- Journal :
- BMJ Open Diabetes Research & Care
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.80ec367701a14461892c8ad8b3ccebb4
- Document Type :
- article
- Full Text :
- https://doi.org/10.1136/bmjdrc-2023-003510