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Activity of 2-benzyl-1-(2-hydroxyethyl)-5-nitroindazolin-3-one on Trypanosoma cruzi Bloodstream Trypomastigotes (Y strain): In Vitro and In Vivo Studies

Authors :
Cristina Fonseca-Berzal
Cristiane França da Silva
Marcos Meuser Batista
Francisca Hildemagna Guedes-da-Silva
Mariane Vasconcelos
Kelly C. Demarque
José A. Escario
Vicente J. Arán
Maria de Nazaré C. Soeiro
Alicia Gómez-Barrio
Source :
Proceedings, Vol 1, Iss 6, p 655 (2017)
Publication Year :
2017
Publisher :
MDPI AG, 2017.

Abstract

Benznidazole and nifurtimox, the currently available drugs for the specific treatment of Chagas disease, show limited effectiveness and high toxicity that prompt the identification of therapeutic alternatives. [...]

Subjects

Subjects :
n/a
General Works

Details

Language :
English
ISSN :
25043900
Volume :
1
Issue :
6
Database :
Directory of Open Access Journals
Journal :
Proceedings
Publication Type :
Academic Journal
Accession number :
edsdoj.81a0dfbbdf74a4084bf5ddef2f4bddb
Document Type :
article
Full Text :
https://doi.org/10.3390/proceedings1060655