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Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC

Authors :
Bin Qiu
Wei Guo
Fan Zhang
Fang Lv
Ying Ji
Yue Peng
Xiaoxi Chen
Hua Bao
Yang Xu
Yang Shao
Fengwei Tan
Qi Xue
Shugeng Gao
Jie He
Source :
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Publication Year :
2021
Publisher :
Nature Portfolio, 2021.

Abstract

ctDNA has been shown to identify minimal residual disease (MRD) and is thus dynamically monitored in different types of tumours. Here, the authors show that serial longitudinal ctDNA analysis can be used as a tool to detect MRD, inform the use of adjuvant therapy, and predict recurrence risk in lung cancer.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
12
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.81a588d43ab74ba19c66aa4fd177b6f2
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-021-27022-z