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Drug Repositioning in Glioblastoma: A Pathway Perspective

Authors :
Sze Kiat Tan
Anna Jermakowicz
Adnan K. Mookhtiar
Charles B. Nemeroff
Stephan C. Schürer
Nagi G. Ayad
Source :
Frontiers in Pharmacology, Vol 9 (2018)
Publication Year :
2018
Publisher :
Frontiers Media S.A., 2018.

Abstract

Glioblastoma multiforme (GBM) is the most malignant primary adult brain tumor. The current standard of care is surgical resection, radiation, and chemotherapy treatment, which extends life in most cases. Unfortunately, tumor recurrence is nearly universal and patients with recurrent glioblastoma typically survive

Details

Language :
English
ISSN :
16639812
Volume :
9
Database :
Directory of Open Access Journals
Journal :
Frontiers in Pharmacology
Publication Type :
Academic Journal
Accession number :
edsdoj.81ec3064cb4947aca1d199a77b817f16
Document Type :
article
Full Text :
https://doi.org/10.3389/fphar.2018.00218