Back to Search Start Over

Quorum Sensing Inhibitory Activity of Giganteone A from Myristica cinnamomea King against Escherichia coli Biosensors

Authors :
Yasodha Sivasothy
Thiba Krishnan
Kok-Gan Chan
Siti Mariam Abdul Wahab
Muhamad Aqmal Othman
Marc Litaudon
Khalijah Awang
Source :
Molecules, Vol 21, Iss 3, p 391 (2016)
Publication Year :
2016
Publisher :
MDPI AG, 2016.

Abstract

Malabaricones A–C (1–3) and giganteone A (4) were isolated from the bark of Myristica cinnamomea King. Their structures were elucidated and characterized by means of NMR and MS spectral analyses. These isolates were evaluated for their anti-quorum sensing activity using quorum sensing biosensors, namely Escherichia coli [pSB401] and Escherichia coli [pSB1075], whereby the potential of giganteone A (4) as a suitable anti-quorum sensing agent was demonstrated.

Details

Language :
English
ISSN :
14203049 and 21030391
Volume :
21
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
edsdoj.82bb93794755401783d60921c5ef4cbd
Document Type :
article
Full Text :
https://doi.org/10.3390/molecules21030391