P130 TEST-RETEST RELIABILITY FOR PULSE WAVE VELOCITY AND CARDIO-ANKLE VASCULAR INDEX AMONG AFRO-CARIBBEAN YOUNG ADULTS

Background: This study evaluated the test-retest reliability of carotid-femoral pulse wave velocity (PWV) and cardio-ankle vascular index (CAVI) among young adults in Jamaica. Methods: We recruited participants from the Jamaica 1986 Birth Cohort Study. PWV was measured using the Arteriograph device™ (TensioMed, Budapest) and CAVI with the VaSera™ device (Fukuda Denshi, Tokyo). Both measurements were done twice on the same day with a 1-hour interval between measurements. Test-retest reliability was estimated using the intra-class correlation coefficient (ICC) and Bland-Altman plots. Kappa statistic was used to assess agreement between repeated tests in classifying participants as high PWV or CAVI, defined as being in the upper tertile of measurements. Results: Analyses included 89 participants (43 males; 46 females; mean age 28.4±0.50 years). Mean PWV for first and second readings were 6.56 cm/s and 6.64 cm/s, respectively (mean difference −0.08 [95%CI −0.18, 0.03, p = 0.142]). Mean values for first and second CAVI were 6.53 and 6.20, respectively, (mean difference 0.34 [95%CI 0.18, 0.50, p < 0.001]). ICC for PWV was 0.88 (95%CI 0.83, 0.92) and for CAVI 0.57 (95%CI 0.41, 0.69). Bland-Altman plots indicated that measurements taken from both devices were highly reproducible, with most points (85/89 for PWV; 86/89 for CAVI) falling within 2 SD of the mean difference. Kappa statistic was 0.76 for PWV and 0.56 for CAVI. Conclusion: PWV (Arteriograph™) and CAVI (VaSera™) have good test-retest reliability among Jamaican youth adults; however repeated CAVI values were marginally lower than the first measurement and the ICC and kappa estimates were lower.