Circulating Biomarkers in Hypertrophic Cardiomyopathy

Authors :: Eldon L. Matthia
Michael L. Setteducato
Mohammed Elzeneini
Nicholas Vernace
Michael Salerno
Christopher M. Kramer
Ellen C. Keeley
Source :: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 23 (2022)
Publication Year :: 2022
Publisher :: Wiley, 2022.
Abstract: Hypertrophic cardiomyopathy is the most common genetic heart disease. Biomarkers, molecules measurable in the blood, could inform the clinician by aiding in diagnosis, directing treatment, and predicting outcomes. We present an updated review of circulating biomarkers in hypertrophic cardiomyopathy representing key pathologic processes including wall stretch, myocardial necrosis, fibrosis, inflammation, hypertrophy, and endothelial dysfunction, in addition to their clinical significance.

Subjects :: biomarker
cardiac imaging
hypertrophic cardiomyopathy
Diseases of the circulatory (Cardiovascular) system
RC666-701

Language :: English
ISSN :: 20479980
Volume :: 11
Issue :: 23
Database :: Directory of Open Access Journals
Journal :: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Publication Type :: Academic Journal
Accession number :: edsdoj.834f67e65dd64fb89f5e37bce487d345
Document Type :: article
Full Text :: https://doi.org/10.1161/JAHA.122.027618