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Enantiomeric Cephalotaxus alkaloids from seeds of Cephalotaxus oliveri
- Source :
- Natural Products and Bioprospecting, Vol 12, Iss 1, Pp 1-7 (2022)
- Publication Year :
- 2022
- Publisher :
- SpringerOpen, 2022.
-
Abstract
- Abstract Five undescribed alkaloids were isolated from the seeds of Cephalotaxus oliveri along with 27 known ones. The new structures were elucidated based on spectroscopic data including 1D and 2D NMR, MS and calculated ECD spectra. Among them, (+)-acetylcephalofortine C was an enantiomeric Cephalotaxine alkaloids. The performed bioassay revealed that those alkaloids were not cytotoxic against cancer cells and had no neuroprotective properties in the HEI-OC-1 cells model.
- Subjects :
- Cephalotaxus oliveri
Cephalotaxaceae
Alkaloid
Enantiomer
Botany
QK1-989
Subjects
Details
- Language :
- English
- ISSN :
- 21922195 and 21922209
- Volume :
- 12
- Issue :
- 1
- Database :
- Directory of Open Access Journals
- Journal :
- Natural Products and Bioprospecting
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.83aea178eb57467fa2e6522a20991c6c
- Document Type :
- article
- Full Text :
- https://doi.org/10.1007/s13659-022-00344-1