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Histone macroH2A1 is a stronger regulator of hippocampal transcription and memory than macroH2A2 in mice

Authors :
Gurdeep Singh
Gilda Stefanelli
Klotilda Narkaj
Mark A. Brimble
Samantha D. Creighton
Timothy A. B. McLean
Meaghan Hall
Krista A. Mitchnick
Jacqueline Zakaria
Thanh Phung
Anas Reda
Amanda M. Leonetti
Ashley Monks
Lara Ianov
Boyer D. Winters
Brandon J. Walters
Andrew M. Davidoff
Jennifer A. Mitchell
Iva B. Zovkic
Source :
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

The structurally-unique histone variant, mH2A1, influences learning and memory in mice to a greater extent than a similar variant, mH2A2.

Subjects

Subjects :
Biology (General)
QH301-705.5

Details

Language :
English
ISSN :
23993642
Volume :
5
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Communications Biology
Publication Type :
Academic Journal
Accession number :
edsdoj.840a5d938684f1fae4467b25c62e8a3
Document Type :
article
Full Text :
https://doi.org/10.1038/s42003-022-03435-4