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Enantioselective construction of ortho-sulfur- or nitrogen-substituted axially chiral biaryls and asymmetric synthesis of isoplagiochin D

Authors :
He Yang
Wenjun Tang
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Ortho-heteroatom-substituted axially chiral biaryls are valuable structures in synthetic and medicinal chemistry. Here, the authors established an efficient synthesis of these chiral structures via asymmetric cross-coupling.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.8506800cdb64531a0ee6f54e538dd48
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-32360-7