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Trends in Paper-Based Sensing Devices for Clinical and Environmental Monitoring

Authors :
Shekher Kummari
Lakshmi R. Panicker
Jagadeeswara Rao Bommi
Sampath Karingula
Venisheety Sunil Kumar
Kuldeep Mahato
Kotagiri Yugender Goud
Source :
Biosensors, Vol 13, Iss 4, p 420 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Environmental toxic pollutants and pathogens that enter the ecosystem are major global issues. Detection of these toxic chemicals/pollutants and the diagnosis of a disease is a first step in efficiently controlling their contamination and spread, respectively. Various analytical techniques are available to detect and determine toxic chemicals/pathogens, including liquid chromatography, HPLC, mass spectroscopy, and enzyme-linked immunosorbent assays. However, these sensing strategies have some drawbacks such as tedious sample pretreatment and preparation, the requirement for skilled technicians, and dependence on large laboratory-based instruments. Alternatively, biosensors, especially paper-based sensors, could be used extensively and are a cost-effective alternative to conventional laboratory testing. They can improve accessibility to testing to identify chemicals and pollutants, especially in developing countries. Due to its low cost, abundance, easy disposal (by incineration, for example) and biocompatible nature, paper is considered a versatile material for the development of environmentally friendly electrochemical/optical (bio) sensor devices. This review presents an overview of sensing platforms constructed from paper, pointing out the main merits and demerits of paper-based sensing systems, their fabrication techniques, and the different optical/electrochemical detection techniques that they exploit.

Details

Language :
English
ISSN :
20796374
Volume :
13
Issue :
4
Database :
Directory of Open Access Journals
Journal :
Biosensors
Publication Type :
Academic Journal
Accession number :
edsdoj.852ba9ef3c24e01bbad004492e85f5e
Document Type :
article
Full Text :
https://doi.org/10.3390/bios13040420