Expression levels of MIF, NLRP1 and FOXP3 genes along with biomarker levels in patients with active form of non-segmental generalized vitiligo: A study in South Indian population

Vitiligo, the most widespread hypopigmentary syndrome, is considered to be a multifactorial disease in which the active melanocytes are lost. Vitiligo has been studied in a variety of ways, and several genes have been implicated. In this study we focused on investigating biomarker levels of TNF-α, MDA and TAS by using ELISA, and along with that mRNA expression levels of MIF, NLRP1 and FoxP3 genes were quantified with qRT-PCR. In expression studies, Non-segmental Generalized Vitiligo (NSV) subjects had a substantial (P