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A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia

Authors :
Kaustubh Adhikari
Javier Mendoza-Revilla
Anood Sohail
Macarena Fuentes-Guajardo
Jodie Lampert
Juan Camilo Chacón-Duque
Malena Hurtado
Valeria Villegas
Vanessa Granja
Victor Acuña-Alonzo
Claudia Jaramillo
William Arias
Rodrigo Barquera Lozano
Paola Everardo
Jorge Gómez-Valdés
Hugo Villamil-Ramírez
Caio C. Silva de Cerqueira
Tábita Hunemeier
Virginia Ramallo
Lavinia Schuler-Faccini
Francisco M. Salzano
Rolando Gonzalez-José
Maria-Cátira Bortolini
Samuel Canizales-Quinteros
Carla Gallo
Giovanni Poletti
Gabriel Bedoya
Francisco Rothhammer
Desmond J. Tobin
Matteo Fumagalli
David Balding
Andrés Ruiz-Linares
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Pigmentation variation in humans is influenced by complex genetic architecture in different populations. Here, the authors perform a genome-wide association analysis involving > 6,000 Latin Americans for pigmentation of skin and eyes, and identify known and novel genetic associations.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.86c730a9ce5e412d8c65dc5984f7c306
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-08147-0