Back to Search
Start Over
Enhanced circulating levels of CD3 cells-derived extracellular vesicles in different forms of pulmonary hypertension
- Source :
- Pulmonary Circulation, Vol 9 (2019)
- Publication Year :
- 2019
- Publisher :
- Wiley, 2019.
-
Abstract
- It has been shown previously that increased circulating endothelial cells-derived extracellular vesicles represent an important pathological attribute of pulmonary hypertension. Although it is a well-known fact that inflammatory cells may also release extracellular vesicles, and pulmonary hypertension is a disease associated with abnormal inflammation, there is no profound knowledge with regard to the role of inflammatory cells-derived extracellular vesicles. Therefore, our study demonstrated that circulating levels of extracellular vesicles derived from T-cells are enhanced in various pulmonary hypertension forms and that endothelial cells-derived extracellular vesicles may have distinctive profiles in different clinical subgroups of pulmonary hypertension, which still remains as a poorly treatable and life-threatening disorder.
Details
- Language :
- English
- ISSN :
- 20458940
- Volume :
- 9
- Database :
- Directory of Open Access Journals
- Journal :
- Pulmonary Circulation
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.877b02aebd514c459b58e6c8cbb0cbfc
- Document Type :
- article
- Full Text :
- https://doi.org/10.1177/2045894019864357